VDSpher® MS Column Line

New VDSpher® MS Line for LC-MS/MS

Mass spectrometry is being used by an increased number of clinical laboratories to handle small sample volumes in order to detect and quantify very small concentrations of a given analyte such as Vitamin D2/D3, Immunosuppressants, etc. The HPLC column is an essential part of an LC-MS/MS configuration and needs to fulfill certain criteria:

  • Particle size of 2.5 μm if a high resolution is needed.
  • Particel size of 4.0 μm if the resolution is not an issue.

Since Mass Spectrometry is a highly sensitive method, very small impurities can be detected (e.g. due to carry-over effects), the VDSpher® MS phases were specifically designed in order to avoid these carry-over effects.

We are introducing 10 different modifications of the VDSpher® MS line.

The C18 phases can be used for a broad range of

  • hydrophilic (C18-H, C18-LC-H) and
  • hydrophobic (C18-DE, C18-B-DE) applications.

The non-endcapped phase C18-B shows a medium hydrophobicity.

In addition, we offer

  • hydrophobic VDSpher® MS-Phases with C8, C4, Phenyl und CN- modifications.

The pore diameter of all VDSpher® MS-Phases is 100 Å and the column dimensions available are 30-150 mm length and 2.0 - 4.6 mm ID. Longer columns are available upon request.

Phase

Endcapping

pH Range

USP-Code

VDSpher®  MS 100 C18-DE

Yes

2 – 9

L1

VDSpher®  MS 100 C18-B

No

2 – 7.5

L1

VDSpher®  MS 100 C18-B-DE

Yes

2 – 10

L1

VDSpher®  MS 100 C18-H

Polar

2 – 7.5

L1

VDSpher®  MS 100 C18-LC-H

Hydrophilic

2 – 8

L1

VDSpher®  MS 100 C8-B-DE

Yes

2 – 10

L7

VDSpher®  MS 100 C4-B-DE

Yes

2 – 9

L26

VDSpher®  MS 100 Phenyl-DE

Yes

2 – 9

L11

VDSpher®  MS 100 CN-DE

Yes

2 – 9

L10

VDSpher®  MS 100 CN-DE-RP

Yes

2 – 9

L10

VDSpher® MS 100 HPLC-Columns Phase Codes

Phase

Particle Size: 2.5 μm

Particle Size: 4.0 μm

C18-DE

E18BVMF

E18BVMI

C18-B

E189VMF

E189VMI

C18-B-DE

E18DVMF

E18DVMI

C18-H

E184VMF

E184VMI

C18-LC-H

E18HVMF

E18HVMI

C8-B-DE

E08DVMF

E08DVMI

C4-B-DE

E04DVMF

E04DVMI

Phenyl-DE

E05BVMF

E05BVMI

CN-DE

E20BVMF

E20BVMI

CN-DE-RP

E21BVMF

E21BVMI

VDSpher® ME 100 - Columns & Guard Cartridges / Dimension Codes

ID in mm

Length in mm

Dimension Code

2.0

30

N0320…

33

N0420…

50

N0520…

53

N0620…

75

N0720…

100

N1020…

125

N1320…

150

N1520…

3.0

30

N0330…

33

N0430…

50

N0530…

53

N0630…

75

N0730…

100

N1030…

125

N1330…

150

N1530…

4.0

30

N0340…

33

N0440…

50

N0540…

53

N0640…

75

N0740…

100

N1040…

125

N1340…

150

N1540…

4.6

30

N0346…

33

N0446…

50

N0546…

53

N0646…

75

N0746…

100

N1046…

125

N1346…

150

N1546…

2.0

5

V0520…

10

V1020…

4.0

5

V0540…

10

V1040…

Example: VDSpher® MS 100 C18-B 2.5 μm, 50 x 2.0 mm

Dimension Code: N0520 + Phase Code: E189VMF

Order No.: N0520E189VMF

For further information please contact us at info@iristech.net.