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Mynox® Gold:
Mycoplasma Elimination, 2 in 1 - Double Strength


Cat.-No. 10-0201              2 Applications
Cat.-No. 10-0501              5 Applications
Cat.-No. 10-1001              10 Applications

Mynox Gold Description
Mynox®Gold represents the further development of the classical Mynox®, which was known for a very high elimination efficiency and low cytotoxicity. Mynox®Gold is a combination of a standard antibiotic and a biological reagent. One application comprises of 4 vials, a starter treatment and three main treatments. The starter treatment kills most of the mycoplasma particles without harming the cells. The main treatment kills all remaining mycoplasma leading to a permanent eradication with efficiency rates up to 100 %. One application can be used to cure one cell culture permanently from mycoplasma burden.


Mynox_Gold

No cytotoxicity
Cytotoxicity is basically not detectable for most cell types. Most cell lines do not show any changes in morphology during treatment.

Highly effective
The ratio for a permanent eradication is close to 100 %.

Universal for cell lines
Mynox®Gold can be used for any cell type without restriction. Only cells harboring Chlamydia or other bacteria as host systems can not be treated. The antibiotic portion of the product might affect the integrated microorganisms.

Universal for mycoplasma
Any type of microorganisms belonging to the group of Mollicutes, including the Mycoplasma, Spiroplasma, Acholeplasma, Ureaplasma, etc. can be success fully treated with Mynox®Gold.

Low resistance risk
Due to the combination of an antibiotic and a reagent showing a biophysical mode of action directly killing the mycoplasma, formation of resistances against Mynox®Gold is most unlikely.

Format
Mynox®Gold contains 1 vial for the starter treatment and 3 vials for the main treatment. Each vial contains 500 μl as a sterile, ready-to-use solution.

Interoperable
Mynox®Gold can be used with anti biotic selection agents, for example G418, blastocyclin, and hygromycin. It also does not interfere with killer genes turned on by tetramycin or doxycyclin.

Mynox®Gold is intended for research use only. Not recommended for clinical treatment.
Store the original container at temperatures of +2 to + 8 °C.

 

Mynox_Gold

Cytotoxicity of Mynox®Gold on contami nated cells. Adherent cell lines were treated with Mynox®Gold according to the protocol 4 days of incubation. The cultures were in activated and stained as described by Flick & Gifford. Untreated cultures had been used as reference (100 %).

 


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